N. Korean Missile Hits Target of Alarming the World

North Korea's successful launch of an intercontinental ballistic missile hit its target: it bolstered the standing of its young tyrant Kim Jong Un and raised the specter of being able to eventually strike the U.S. with a nuclear weapon.

The pride in the success of the launch -- after several failures -- is a huge boost for Kim Jong Un, 29, who took power one year ago. He has been trying to cement his authority and win the hearts of the people with soft social and economic reforms, like allowing women to wear pants or more small businesses to operate based on profit.

But the rocket launch was on a different scale. A North Korean female announcer in a pink and dark grey national costume excitedly read an announcement of the missile's success and national TV aired interviews with people jumping and cheering on the news.

There had been reservations within and outside of North Korea when Kim Jong Un took power after his father's death on Dec. 17 last year as to whether the young Kim could lead a nuclear state. Looking determined at his first official appearance earlier this year, he had pledged to fulfill the legacy of his father Kim Jong Il to become a "self-sufficient strong nation" with space rocket technology.

The missile is believed to have a range of 6,212 miles, enough distance to reach the west coast of the United States. Its existence, along with a small North Korean nuclear arsenal, is an alarming possibility for many.

PHOTOS: An Inside Look At North Korea

North Korea, however, says it was simply putting a satellite in orbit.

"Picking on our launch (and not others) accusing that ours is a long-range missile and a provocative act causing instability comes from seeing us from a hostile point of view," said North Korea's foreign ministry in an official statement. "We do not want this to be overblown into something that none of us intended to be and hope all related nations act with reason and calmness."

But North Korean denials carry little credibility.

This evidence that North Korea has mastered the long-range missile technology does not mean there will be an imminent nuclear threat.

"They haven't figured out how to weaponize a nuclear (bomb) that will fit in a missile, nor do they have accurate guidance at long ranges," said Stephen Ganyard, ABC News consultant and former deputy assistant secretary of state.

Another crucial technology North Korea is yet to achieve is a proper heat shielding required to protect the warhead while re-entering the earth's atmosphere.

"This is a big leap for Pyongyang. They have been a threat with potential capability. But now a new era begins as a threat with possible capability," said Hwee-Rhak Park, professor of political leadership at Kookmin University in Seoul.

There was obvious alarm, however, as the international community condemned the launch, as North Korea is banned from developing nuclear and missile-related technology under U.N. resolutions.

South Korean President Lee Myung-Bak convened an emergency national security meeting. Japan's envoy to the United Nations called for consultations on the launch within the U.N. Security Council. Russian Foreign Ministry said it "has caused us deep regret," and even China "expressed regret," a significant notch up in condemnation from previous statements on North Korea, its traditional ally.

That international attention, analysts in Seoul say, is exactly what North Korea wanted.

Read More..

North Korea's new leader burnishes credentials with rocket

SEOUL/TOKYO (Reuters) - North Korea successfully launched a rocket on Wednesday, boosting the credentials of its new leader and stepping up the threat the isolated and impoverished state poses to its opponents.

The rocket, which North Korea says put a weather satellite into orbit, has been labeled by the United States, South Korea and Japan as a test of technology that could one day deliver a nuclear warhead capable of hitting targets as far as the continental United States.

"The satellite has entered the planned orbit," a North Korean television news-reader clad in traditional Korean garb triumphantly announced, after which the station played patriotic songs with the lyrics "Chosun (Korea) does what it says".

The rocket was launched just before 10 a.m. Korea time (01000 GMT), according to defense officials in South Korea and Japan, and easily surpassed a failed April launch that flew for less than two minutes.

The North American Aerospace Defense Command (NORAD) said that it "deployed an object that appeared to achieve orbit", the first time an independent body has verified North Korean claims.

North Korea followed what it said was a similar successful launch in 2009 with a nuclear test that prompted the United Nations Security Council to stiffen sanctions that it originally imposed in 2006 after the North's first nuclear test.

The state is banned from developing nuclear and missile-related technology under U.N. resolutions, although Kim Jong-un, the youthful head of state who took power a year ago, is believed to have continued the state's "military first" programmes put into place by his deceased father Kim Jong-il.

North Korea lauded Wednesday's launch as celebrating the prowess of all three Kims to rule since it was founded in 1948.

"At a time when great yearnings and reverence for Kim Jong-il pervade the whole country, its scientists and technicians brilliantly carried out his behests to launch a scientific and technological satellite in 2012, the year marking the 100th birth anniversary of President Kim Il Sung," its KCNA news agency said.

Washington condemned Wednesday's launch as a "provocative action" and breach of U.N. rules, while Japan's U.N. envoy called for a Security Council meeting. However, diplomats say further tough sanctions are unlikely to be agreed at the body as China, the North's only major ally, will opppose them.

"The international community must work in a concerted fashion to send North Korea a clear message that its violations of United Nations Security Council resolutions have consequences," the White House said in a statement.

U.S. intelligence has linked North Korea with missile shipments to Iran. Newspapers in Japan and South Korea have reported that Iranian observers were in the North for the launch, something Iran has denied.

Japan's likely next prime minister, Shinzo Abe, who is leading in opinion polls ahead of an election on December 16 and who is known as a North Korea hawk, called on the United Nations to adopt a resolution "strongly criticizing" Pyongyang.

BEIJING BLOCK

China had expressed "deep concern" prior to the launch which was announced a day after a top politburo member, representing new Chinese leader Xi Xinping, met Kim Jong-un in Pyongyang.

On Wednesday its tone was measured, regretting the launch but calling for restraint on possible counter-measures, in line with previous policy when it has effectively vetoed tougher sanctions.

"China believes the Security Council's response should be cautious and moderate, protect the overall peaceful and stable situation on the Korean peninsula, and avoid an escalation of the situation," Chinese Foreign Ministry spokesman Hong Lei told journalists.

Bruce Klingner, a Korea expert at the Heritage Foundation, told a conference call: "China has been the stumbling block to firmer U.N. action and we'll have to see if the new leadership is any different than its predecessors."

A senior adviser to South Korea's president said last week it was unlikely there would be action from the U.N. and that Seoul would expect its allies to tighten sanctions unilaterally.

Kim Jong-un, believed to be 29 years old, took power when his father died on December 17 last year and experts believe the launch was intended to commemorate the first anniversary of the death.

The April launch was timed for the centennial of the birth of Kim Il Sung, the grandfather of its current ruler.

Wednesday's success puts the North ahead of the South which has not managed to get a rocket off the ground.

"This is a considerable boost in establishing the rule of Kim Jong-un," said Cho Min, an expert at the Korea Institute of National Unification.

There have been few indications the secretive and impoverished state, where the United Nations estimates a third of the population is malnourished, has made any advances in opening up economically over the past year.

North Korea remains reliant on minerals exports to China and remittances from tens of thousands of its people working on labor projects overseas.

The 22 million population often needs handouts from defectors who have escaped to South Korea in order to afford basic medicines.

Given the puny size of its economy - per capita income is less than $2,000 a year - one of the few ways the North can attract world attention is by emphasizing its military threat.

Pyongyang wants the United States to resume aid and to recognize it diplomatically, although the April launch scuppered a planned food deal.

It is believed to be some years away from developing a functioning nuclear warhead although it may have enough plutonium for around half a dozen nuclear bombs, according to nuclear experts.

The North has also been enriching uranium, which would give it a second path to nuclear weapons as it sits on vast natural uranium reserves.

"A successful launch puts North Korea closer to the capability to deploy a weaponised missile," said Denny Roy, a senior fellow at the East-West Center in Hawaii.

"But this would still require fitting a weapon to the missile and ensuring a reasonable degree of accuracy. The North Koreans probably do not yet have a nuclear weapon small enough for a missile to carry."

Pyongyang says that its development is part of a civil nuclear programme, but has also boasted of it being a "nuclear weapons power".

(Additional reporting by Jumin Park and Yoo Choonsik in SEOUL; David Alexander, Matt Spetalnick and Paul Eckert in WASHINGTON; Linda Sieg in TOKYO; Sui-Lee Wee in BEIJING; Rosmarie Francisco in MANILA; Writing by David Chance; Editing by Raju Gopalakrishnan)

Read More..

Boxing: Philippines' Pacquiao promises to 'rise again'

MANILA: Philippines boxing icon Manny Pacquiao vowed to "rise again" as he flew home Wednesday after a brutal knockout defeat that prompted some fans and experts to urge him to retire.

"Don't worry, we will rise again," he told well-wishers as arrived in Manila from the United States, where he suffered his second consecutive loss with a sixth-round knockout by Mexican Juan Manuel Marquez on Saturday.

Pacquiao, who has 54 wins, five defeats and two draws in nearly 18 years in the pro ring, lost his World Boxing Organization welterweight crown in June on a controversial points decision to unbeaten US fighter Timothy Bradley.

But retirement appears far from the mind of Pacquiao, who turns 34 on Monday and was once regarded as the world's best pound-for-pound fighter.

"I watched a replay of my fight and I am satisfied with my movement," said Pacquiao.

"I was fighting very well from the first to the sixth round. I was moving well. It was just that I got hit with a lucky punch on the last second of the round."

Pacquiao, who on Wednesday also announced he was donating US$244,000 to the victims of a typhoon which devastated the Philippines' south last week, said he had been looking to finish off Marquez by the eighth round.

"The way the fight was going, there was no way it would have reached the 12th round," he said.

He cited how he had broken the Mexican's nose, leaving him with breathing difficulties that Pacquiao claimed had forced his foe to remove his mouthpiece at one point.

But Pacquiao acknowledged: "He owned that night. Let's give him due credit."

Former world champion Ricky Hatton, who was knocked out by Pacquiao in May 2009, has added his voice to calls for the Filipino to hang up his gloves.

"The only advice I could give Manny Pacquiao is that his legacy is already secured," said the Briton, a former world light-welterweight and welterweight champion who retired for a second time last month.

"The thing is with us fighters is that there is always one more fight," the 34-year-old told AFP during a visit to Hong Kong.

"What's he (Pacquiao) going to achieve by having one more fight? Probably nothing. He's an eight-weight world champion. There's nothing more to be said."

Hatton, who was knocked out in a failed return to the ring in November, in what he says was his last fight, said of his Filipino rival: "You'd like to see him go into retirement and spend some time with his family and be happy.

"He can't do any more from a boxing point of view."

- AFP/jc

Read More..

Mayawati warns government of tougher stand, says outburst against Ansari 'first step'

NEW DELHI: Accusing the government of not being serious in passing the bill for providing quota for SC/STs in promotions in government jobs, BSP chief Mayawati threatened to take a "tougher" stand, saying her Wednesday's "outburst" in Rajya Sabha was only "the first step".

BSP had stalled proceedings in both Houses of Parliament on Wednesday and Mayawati had questioned Rajya Sabha chairman Hamid Ansari for not initiating action against those members who were disrupting business in the House.

"I had said two days ago that BSP would adopt a 'tough' stand. It is the responsibility of the government and the Rajya Sabha chairman to bring the House in order...Today's (outburst) was our first tough stand in Rajya Sabha. We will take our next stand at an appropriate time," Mayawati told reporters outside Parliament House.

She accused the government of not being serious on the passage of the SC/ST quota bill.

"If the government is actually serious about the passage of the bill and other public interest legislations, then the government as well as the chairman should see that the House should function in order," she said.

Earlier, the BSP chief shocked the Rajya Sabha by telling chairman Hamid Ansari that he is "not seen" in the House in the afternoon after which the House is not allowed to function.

"I am not ready to listen to anything. We have seen in the last few days that every day the House is not allowed to function after 12pm. It is your responsibility to ensure that it functions. Who will ensure that it functions," she told the Chair from the Well as also from her seat.

"You are not seen here after 12pm... What kind of House is this? You have to take decision that what has to be done for this (ensuring the functioning of the House)," the BSP chief said.

She was protesting against the frequent disruption over a Bill for providing reservation in promotion to SC/STs in government jobs, an issue that has seen the party at loggerheads with the Samajwadi Party, its arch detractor in UP politics.

The protest by the BSP on the quota issue saw the House being adjourned twice before lunch.

Mayawati's remarks left the House stunned. The chairman told her that she was a senior leader and should allow the House to function. He said it was the responsibility of everyone to let the House function.

But, BSP members were unrelenting.

Mayawati's outburst came at 11.30pm when minister Anand Sharma was replying to a query on the plight of weavers in Uttar Pradesh.

The BSP supremo, along with her party colleagues, came into House and started speaking even before taking her seat.

As the chairman tried to pacify Mayawati and asked her to allow the question hour to proceed, the BSP chief went into the Well with her party members continuing with her verbal attack.

Read More..

DA investigating Texas' troubled $3B cancer agency

AUSTIN, Texas (AP) — Turmoil surrounding an unprecedented $3 billion cancer-fighting effort in Texas worsened Tuesday when its executive director offered his resignation and the state's chief public corruption prosecutor announced an investigation into the beleaguered agency.

No specific criminal allegations are driving the latest probe into the Cancer Prevention and Research Institute of Texas, said Gregg Cox, director of the Travis County district attorney's public integrity unit. But his influential office opened a case only weeks after the embattled agency disclosed that an $11 million grant to a private company bypassed review.

That award is the latest trouble in a tumultuous year for CPRIT, which controls the nation's second-largest pot of cancer research dollars. Amid the mounting problems, the agency announced Tuesday that Executive Director Bill Gimson had submitted his letter of resignation.

"Unfortunately, I have also been placed in a situation where I feel I can no longer be effective," Gimson wrote in a letter dated Monday.

Gimson said the troubles have resulted in "wasted efforts expended in low value activities" at the agency, instead of a focused fight against cancer. Gimson offered to stay on until January, and the agency's board must still approve his request to step down.

His departure would complete a remarkable house-cleaning at CPRIT in a span of just eight months. It began in May, when Dr. Alfred Gilman resigned as chief science officer in protest over a different grant that the Nobel laureate wanted approved by a panel of scientists. He warned it would be "the bomb that destroys CPRIT."

Gilman was followed by Chief Commercialization Officer Jerry Cobbs, whose resignation in November came after an internal audit showed Cobbs included an $11 million proposal in a funding slate without a required outside review of the project's merits. The lucrative grant was given to Dallas-based Peloton Therapeutics, a biomedical startup.

Gimson chalked up Peloton's award to an honest mistake and has said that, to his knowledge, no one associated with CPRIT stood to benefit financially from the company receiving the taxpayer funds. That hasn't satisfied some members of the agency's governing board, who called last week for more assurances that no one personally profited.

Cox said he has been following the agency's problems and his office received a number of concerned phone calls. His department in Austin is charged with prosecuting crimes related to government officials; his most famous cases include winning a conviction against former U.S. House Majority Leader Tom DeLay in 2010 on money laundering charges.

"We have to gather the facts and figure what, if any, crime occurred so that (the investigation) can be focused more," Cox said.

Gimson's resignation letter was dated the same day the Texas attorney general's office also announced its investigation of the agency. Cox said his department would work cooperatively with state investigators, but he made clear the probes would be separate.

Peloton's award marks the second time this year that a lucrative taxpayer-funded grant authorized by CPRIT instigated backlash and raised questions about oversight. The first involved the $20 million grant to M.D. Anderson Cancer Center in Houston that Gilman described as a thin proposal that should have first been scrutinized by an outside panel of scientific peer-reviewers, even though none was required under the agency's rules.

Dozens of the nation's top scientists agreed. They resigned en masse from the agency's peer-review panels along with Gilman. Some accused the agency of "hucksterism" and charting a politically-driven path that was putting commercial product-development above science.

The latest shake-up at CPRIT caught Gilman's successor off-guard. Dr. Margaret Kripke, who was introduced to reporters Tuesday, acknowledged that she wasn't even sure who she would be answering to now that Gimson was stepping down. She said that although she wasn't with the agency when her predecessor announced his resignation, she was aware of the concerns and allegations.

"I don't think people would resign frivolously, so there must be some substance to those concerns," Kripke said.

Kripke also acknowledged the challenge of restocking the peer-review panels after the agency's credibility was so publicly smeared by some of the country's top scientists. She said she took the job because she felt the agency's mission and potential was too important to lose.

Only the National Institutes of Health doles out more cancer research dollars than CPRIT, which has awarded more than $700 million so far.

Gov. Rick Perry told reporters in Houston on Tuesday that he wasn't previously aware of the resignation but said Gimson's decision to step down was his own.

Joining the mounting criticism of CPRIT is the woman credited with brainstorming the idea for the agency in the first place. Cathy Bonner, who served under former Texas Gov. Ann Richards, teamed with cancer survivor Lance Armstrong in selling Texas voters in 2007 on a constitutional amendment to create an unprecedented state-run effort to finance a war on disease.

Now Bonner says politics have sullied an agency that she said was built to fund research, not subsidize private companies.

"There appears to be a cover-up going on," Bonner said.

Peloton has declined comment about its award and has referred questions to CPRIT. The agency has said the company wasn't aware that its application was never scrutinized by an outside panel, as required under agency rules.

___

Follow Paul J. Weber on Twitter: www.twitter.com/pauljweber

Read More..

Gunman 'Tentatively' Identified in Oregon Shooting

A masked gunman who opened fire in the crowded Clackamas Town Center mall in suburban Portland, Ore., killing two individuals before killing himself, has been "tentatively" identified by police, though they have not yet released his name.

The shooter, wearing a white hockey mask, black clothing, and a bullet proof vest, tore through the mall around 3:30 p.m. Tuesday, entering through a Macy's store and proceeding to the food court and public areas spraying bullets, according to witness reports.

Police have not released the names of the deceased. Clackamas County Sheriff's Department Lt. James Rhodes said authorities are in the process of notifying victims' families.

The injured victim has been transported to a local hospital, according to Clackamas County Sheriff Craig Roberts.

PHOTOS: Oregon Mall Shooting

Nadia Telguz, who said she was a friend of the injured victim, told ABC News affiliate KATU-TV in Portland that the woman was expected to recover.

"My friend's sister got shot," Teleguz told KATU. "She's on her way to (Oregon Health and Science University hospital). They're saying she got shot in her side and so it's not life-threatening, so she'll be OK."

Witnesses from the shooting rampage said that a young man who appeared to be a teenager ran through the upper level of Macy's to the mall food court, firing multiple shots, one right after the other, with what is believed to be a black, semi-automatic rifle.

Christopher Onstott/Pamplen Media Group/Portland Tribune

911 Calls From New Jersey Supermarket Shooting Watch Video

More than 10,000 shoppers were at the mall during the day, police said. Roberts said that officers responded to the scene of the shooting within minutes, and four SWAT teams swept the 1.4 million-square-foot building searching for the shooter. He was eventually found dead, an apparent suicide.

"I can confirm the shooter is dead of an apparent self-inflicted gunshot wound," Rhodes said. "By all accounts there were no rounds fired by law enforcement today in the mall."

Roberts said more than 100 law enforcement officers responded to the shooting, and at least four local agencies were working on the investigation, including the FBI and Bureau of Alcohol, Tobacco and Firearms, which is working to trace the shooter's weapon.

READ: Guns in America: A Statistical Look

"For all of us, the mall is supposed to be a place where we can take our families, especially during the holiday season," Roberts said. "Things like this are not supposed to happen."

Roberts also said that shoppers, including two emergency room nurses and one physician who happened to be at the mall, provided medical assistance to victims who had been shot. Other shoppers helped escort individuals out of the mall and out of harm's way, he said.

"There were a huge amount of people running in different directions, and it was chaos for a lot of citizens, but true heroes were stepping up in this time of high stress," Roberts said. "E.R. nurses on the scene were providing medical care to those injured, a physician on the scene was helping provide care to the wounded."

Mall shopper Daniel Martinez told KATU that he had just sat down at a Jamba Juice inside the mall when he heard rapid gunfire. He turned and saw the masked gunman, dressed in all black, about 10 feet away from him.

"I just saw him (the gunman) and thought, 'I need to go somewhere,'" Martinez said. "It was so fast, and at that time, everyone was moving around."

Martinez said he ran to the nearest clothing store. As he ran, he motioned for another woman to follow; several others ran to the store as well, hiding in a fitting room. They stayed there for an hour and a half until SWAT teams told them it was safe to leave the mall.

Read More..

Unknown attackers fire at Cairo protesters, nine hurt

CAIRO (Reuters) - Nine people were hurt when unknown attackers fired at protesters camping at Tahrir Square in central Cairo on Tuesday, according to witnesses and Egyptian media, as opponents and supporters of President Mohamed Mursi's plans to vote on a new constitution geared up for a day of street demonstrations.

Police cars surrounded the square, the first time they had appeared in the area since November 23, shortly after a decree by the Islamist president giving himself sweeping temporary powers touched off widespread protests.

The attackers also threw petrol bombs which started a small fire, witnesses said. Many of the protesters, awakened by the noise, chanted: "The people want the downfall of the regime." Recorded recitations of the Koran were played over speakers in the square.

Leftists, liberals and other opposition groups have called for marches to the presidential palace in the afternoon to protest against the hastily arranged referendum on a new constitution planned for Saturday, which they say is polarizing the country.

Islamists, who dominated the body that drew up the constitution, have urged their followers to turn out "in millions" the same day in a show of support for the president and for a referendum they feel sure of winning and that critics say could put Egypt in a religious straitjacket.

Seven people were killed and hundreds wounded last week in clashes between the Islamist Muslim Brotherhood and opponents besieging Mursi's graffiti-daubed presidential palace.

The elite Republican Guard has yet to use force to keep protesters away from the palace, now ringed with tanks, barbed wire and concrete barricades, but a decree issued by Mursi late on Sunday gives the armed forces the power to arrest civilians during the referendum and until the announcement of the results.

OPPOSITION SAYS MURSI DESTROYING CONSENSUS

Leftist politician Hamdeen Sabahy, one of the most prominent members of the National Salvation Front opposition coalition, said Mursi was driving a wedge between Egyptians and destroying prospects for consensus.

As well as pushing the early referendum, Mursi has angered opponents by taking sweeping temporary powers he said were necessary to secure the country's transition to stability after a popular uprising overthrew autocratic former president Hosni Mubarak 22 months ago.

"The road Mohamed Mursi is taking now does not create the possibility for national consensus," said Sabahy.

If the constitution was passed, he said: "Egypt will continue in this really charged state. It is certain that this constitution is driving us to more political polarization."

The National Salvation Front also includes Nobel Peace Prize laureate Mohamed ElBaradei and former Arab League chief Amr Moussa.

The opposition says the draft constitution fails to embrace the diversity of 83 million Egyptians, a tenth of whom are Christians, and invites Muslim clerics to influence lawmaking.

But debate over the details has largely given way to noisy street protests and megaphone politics, keeping Egypt off balance and ill equipped to deal with a looming economic crisis.

Lamia Kamel, a spokeswoman for Moussa, said the opposition factions were still discussing whether to boycott the referendum or call for a "no" vote.

"Both paths are unwelcome because they really don't want the referendum at all," she said, but predicted a clearer opposition line if the plebiscite went ahead as planned.

Mahmoud Ghozlan, the Muslim Brotherhood's spokesman, said the opposition could stage protests, but should keep the peace.

"They are free to boycott, participate or say no; they can do what they want. The important thing is that it remains in a peaceful context to preserve the country's safety and security."

The army stepped into the conflict on Saturday, telling all sides to resolve their disputes via dialogue and warning that it would not allow Egypt to enter a "dark tunnel".

The continuing disruption is also casting doubts on the government's ability to push through tough economic reforms that form part of a proposed $4.8 billion IMF loan agreement.

(Writing by Edmund Blair; Editing by Will Waterman, Mohammad Zargham and Jim Loney)

Read More..

Mandela has lung infection, says government

 

JOHANNESBURG: Ailing Nelson Mandela has a lung infection but is responding to treatment, South Africa's government said Tuesday, as the revered anti-apartheid icon spent his fourth day in hospital.

"Doctors have concluded the tests, and these have revealed a recurrence of a previous lung infection, for which Madiba is receiving appropriate treatment and he is responding to the treatment," said a statement from President Jacob Zuma's office.

- AFP

Read More..

Time has come to dismiss Parliament: Hazare

NEW DELHI: The time has come to dismiss Parliament, anti-corruption crusader Anna Hazare said on Tuesday while announcing a nationwide tour against the United Progressive Alliance ( UPA) government and graft.

"I will start nationwide tour against government and corruption from Jan 30 from Patna district of Bihar," Hazare told reporters here.

"The time has come to dismiss Parliament. People sitting in Parliament are allowing foreign countries to come to the Indian market," he added.

Hazare was discharged on Monday from the Medanta Medicity Hospital in Gurgaon where he had been admitted after he complained of acidity and stress.

Read More..

New tests could hamper food outbreak detection

WASHINGTON (AP) — It's about to get faster and easier to diagnose food poisoning, but that progress for individual patients comes with a downside: It could hurt the nation's ability to spot and solve dangerous outbreaks.

Next-generation tests that promise to shave a few days off the time needed to tell whether E. coli, salmonella or other foodborne bacteria caused a patient's illness could reach medical laboratories as early as next year. That could allow doctors to treat sometimes deadly diseases much more quickly — an exciting development.

The problem: These new tests can't detect crucial differences between different subtypes of bacteria, as current tests can. And that fingerprint is what states and the federal government use to match sick people to a contaminated food. The older tests might be replaced by the new, more efficient ones.

"It's like a forensics lab. If somebody says a shot was fired, without the bullet you don't know where it came from," explained E. coli expert Dr. Phillip Tarr of Washington University School of Medicine in St. Louis.

The federal Centers for Disease Control and Prevention warns that losing the ability to literally take a germ's fingerprint could hamper efforts to keep food safe, and the agency is searching for solutions. According to CDC estimates, 1 in 6 Americans gets sick from foodborne illnesses each year, and 3,000 die.

"These improved tests for diagnosing patients could have the unintended consequence of reducing our ability to detect and investigate outbreaks, ultimately causing more people to become sick," said Dr. John Besser of the CDC.

That means outbreaks like the salmonella illnesses linked this fall to a variety of Trader Joe's peanut butter might not be identified that quickly — or at all.

It all comes down to what's called a bacterial culture — whether labs grow a sample of a patient's bacteria in an old-fashioned petri dish, or skip that step because the new tests don't require it.

Here's the way it works now: Someone with serious diarrhea visits the doctor, who gets a stool sample and sends it to a private testing laboratory. The lab cultures the sample, growing larger batches of any lurking bacteria to identify what's there. If disease-causing germs such as E. coli O157 or salmonella are found, they may be sent on to a public health laboratory for more sophisticated analysis to uncover their unique DNA patterns — their fingerprints.

Those fingerprints are posted to a national database, called PulseNet, that the CDC and state health officials use to look for food poisoning trends.

There are lots of garden-variety cases of salmonella every year, from runny eggs to a picnic lunch that sat out too long. But if a few people in, say, Baltimore have salmonella with the same molecular signature as some sick people in Cleveland, it's time to investigate, because scientists might be able narrow the outbreak to a particular food or company.

But culture-based testing takes time — as long as two to four days after the sample reaches the lab, which makes for a long wait if you're a sick patient.

What's in the pipeline? Tests that could detect many kinds of germs simultaneously instead of hunting one at a time — and within hours of reaching the lab — without first having to grow a culture. Those tests are expected to be approved as early as next year.

This isn't just a science debate, said Shari Shea, food safety director at the Association of Public Health Laboratories.

If you were the patient, "you'd want to know how you got sick," she said.

PulseNet has greatly improved the ability of regulators and the food industry to solve those mysteries since it was launched in the mid-1990s, helping to spot major outbreaks in ground beef, spinach, eggs and cantaloupe in recent years. Just this fall, PulseNet matched 42 different salmonella illnesses in 20 different states that were eventually traced to a variety of Trader Joe's peanut butter.

Food and Drug Administration officials who visited the plant where the peanut butter was made found salmonella contamination all over the facility, with several of the plant samples matching the fingerprint of the salmonella that made people sick. A New Mexico-based company, Sunland Inc., recalled hundreds of products that were shipped to large retailers all over the country, including Target, Safeway and other large grocery chains.

The source of those illnesses probably would have remained a mystery without the national database, since there weren't very many illnesses in any individual state.

To ensure that kind of crucial detective work isn't lost, the CDC is asking the medical community to send samples to labs to be cultured even when they perform a new, non-culture test.

But it's not clear who would pay for that extra step. Private labs only can perform the tests that a doctor orders, noted Dr. Jay M. Lieberman of Quest Diagnostics, one of the country's largest testing labs.

A few first-generation non-culture tests are already available. When private labs in Wisconsin use them, they frequently ship leftover samples to the state lab, which grows the bacteria itself. But as more private labs switch over after the next-generation rapid tests arrive, the Wisconsin State Laboratory of Hygiene will be hard-pressed to keep up with that extra work before it can do its main job — fingerprinting the bugs, said deputy director Dr. Dave Warshauer.

Stay tuned: Research is beginning to look for solutions that one day might allow rapid and in-depth looks at food poisoning causes in the same test.

"As molecular techniques evolve, you may be able to get the information you want from non-culture techniques," Lieberman said.

___

Follow Mary Clare Jalonick on Twitter at http://twitter.com/mcjalonick

Read More..